Post # 14 07/30/2019 New Information about CBD as a Chemo Treatment

I am a paying member of Consumer Labs, www.consumerlabs.com , an on line source of information about supplements –and they just came out with a report on CBD oil and its uses that changed my thinking about when to administer it to Spirit.

Here are the major takeaways for me in this report:

  1. Most of the research into the value of using CBD oil to treat medical conditions such as cancer is done at very high doses (like 20 mg CBD per kilogram of body weight – about 800 mg/day for Spirit!)– far above my 45-50 mg/day dose I am using for Spirit. However, at these levels, one must start to be concerned about side effects, like affecting kidney function, diarrhea, vomiting, etc.
  2. To be most effective, because CBD is fat soluable, adsorption is 5-15 times higher when given with or right after a high fat meal rather than on an empty stomach! The meal should contain 500-600 calories of fat to be helpful.
  3. With a high fat meal accompanying the CBD, the half life of CBD in the body almost doubles from 24 hours to 39 hours.
  4. CBD at the levels I am giving does not materially aid in sleeping better.
  5. Preliminary science and antidotal evidence suggests CBD does have anti cancer properties and enhances the body’s immune system response to cancer.
  6. There is also early evidence it can help with seizures, pain, anxiety, inflammation and likely other ailments too. Not my focus here, so I will not go into all the data about these conditions.
  7. Half life of CBD in the body, after hitting maximum levels in 2-5 hours, is 18-32 hours and, with continued dosing, much longer than that. So daily dosing, as I am doing with Spirit, would maintain a high level of CBD essentially all the time.
  8. CBD can interact with other medications in a negative way. Too complicated to go into here but one needs to do one’s homework and consult with others before proceeding. In Spirit’s case, he is not on any other meds so clear sailing here.
  9. As to who to buy CBD from, CL offers some information that will be helpful to some I am sure. I am already satisfied I have an excellent source with Nuleaf Naturals and will stick with them.

Based on this information, I am encouraged that the dosing level and schedule is a) not going to do any harm and b) may actually do what I am hoping – that this dose may have a positive impact on cancer metastases in Spirit – no, it not nearly as high as some studies have used but it is significantly higher than the usual – and will be doing it regularly and for a long period of time so…….who knows.

I have also immediately shifted to giving him his CBD dose right after his evening meal rather than at bedtime.

I also have added two heaping tablespoons of coconut oil to his food (worth about ~400 calories of fat). Coupled with the fat content of his regular dog food (Wellness Core dry dog food + Wellness Core canned dog food to hide his daily garlic pills for fleas and ticks + cooked hamburger + boiled egg) am confident I am up in the 500-600 calorie of fat range.

Nothing left to do now but buck up, continue with the program each and every day (practice #10, bucking up).

 

Post #9 06192019

Today, am going to talk about the results of my research into using CBD oil for cancer treatment – for my dog, Spirit.

To review, he had two soft tissue sarcomas, one on his rear leg just above his paw and the other on his lower jaw.

I began my research through www.dogsnaturally.com and articles by Blake Armstrong and took it from there, checking various CBD oil provider websites, www.holistapet.com being one that provided a guide for dosing CBD oil for serious illnesses in dogs. One might want to also check out Armstrong’s website, cannabissupplementsforpets.com .

I finally arrived at 45-50 mg/day for Spirit, a 90 pound dog. I am using the guideline suggested on the Holistapet website for “medicinal use”. Is this the perfect dose for killing cancer cells? No one knows.

As to duration, I arbitrarily decided to do this for about one year.

Why?

In humans, chemotherapy can be over any time period but usually lasts around 6 months. I decided a lot can happen in a year so pick that as a target and see how it goes.

Ultimately, I decided to order $1000 worth of full spectrum organic CO2 extracted CBD oil from www.NuLeaf . It showed up at my door two days later, six dark 50 ml bottles, each one containing 2450 mg of the oil.

After lots of comparing, I chose Nuleaf Naturals because:

  1. a) They had the widest spectrum oil (7 components versus 4 for the others I checked – and since no one knows which components might contribute to activity, right now, more components is better, as far as I am concerned). I discovered this when I compared their analysis to that from other companies.
  2. b) Their product is extracted from their own organically grown hemp in Colorado (provided pesticide and herbicide analyses when requested showing no detectable biocides – can I prove what I have in my hands has the same analysis? No. But at least they have some data – and they sent it to me. The other companies I researched either had no data, or ignored my requests for it, or maybe were not using organically grown hemp or … who knows).
  3. c) Their oil is extracted using carbon dioxide instead of hydrocarbons – more expensive process but no chance of undesirable chemical residues either. (There are other companies using this process too, and some that don’t.)
  4. d) When I called, a human being actually answered the phone, answered my questions, and did what they said they would do when I asked for this information or that data. I was never able to reach a human being at any of the other companies I called.
  5. e) They offer higher concentrations of CBD than many other companies. This was of value to me as I want to administer a relatively concentrated dose of CBD oil in a small volume. With their 2450 mg/50 ml bottle I can squirt a 1 ml dose with a plastic syringe (no needle of course) into his mouth pretty easily.

I’m not suggesting there aren’t other good companies out there – Holista Pet, King Kanine, Hemp Your Pet and surely others too – and some of them even have better websites than Nuleaf (dosing charts for example) but I did not see others with a better product or customer service.

I make zero claims about being an expert about any of this. It is the Wild West out there with little science behind any of it. Does CBD oil actually kill cancer cells? Maybe. What dosing is best? Anyone’s guess.

Still, given the lay of the land here, I am satisfied with my choice.

Tomorrow we go for a checkup at the Animal Cancer and Imaging Center in Canton, Michigan.