Post # 27 05302020

For the past few months, I have been noticing new tumor growth on Spiritdog’s lower jaw and right rear leg, the exact same locations of the original tumors treated with radiation in May, 2019. Subsequent biopsies of both locations confirmed the recurrence (or continuance) of sarcomas. So, sorry to say, the result of treating him with both radiation and fenbendazole has been quite disappointing.

And it is what it is.

I decided to do palliative radiation at the Michigan State University Small Animal Clinic consisting of five treatments, each one a week apart, beginning with last Thursday. The goal is to provide him with more pain free time at a cost of ~ $3000. Is it worth it? Today he acts like a normal healthy middle aged dog, so, for me, the hope of keeping him that way longer makes it a yes.

After the radiation treatments, I will also look into some form of additional treatment even including chemotherapy if I can find a modality that offers minimal side effects with extended quality of life. Maybe metronomic chemotherapy using either cytoxan or Palladia, perhaps alternating it with fenben, perhaps not, or ….. something else?

How am I dealing with this turn of events? Like any human being, I bounce back and forth. I try to follow Spiritdog’s example, living in the present, saturated with appreciation, gratitude and the joy of being with him. In this present, he is acting like a perfectly healthy dog. And sometimes I manufacture stress by sliding into my fear of him dying, even mourning his death, creating stories about the future that obliterate being present, evaporating joy.

As a quick reminder about how our body responds to our stories, from Premier Health, (www.premierhealth.com. Feb 5, 2017): As your body perceives stress, your adrenal glands make and release the hormone cortisol into your bloodstream. Often called the “stress hormone,” cortisol causes an increase in your heart rate and blood pressure.

Fortunately, I can objectively watch myself generating stress because I take my blood pressure daily with my home monitor (usually twice, in the AM and PM). I plot the data on a graph so I can see both how my BP changes daily and over time.

So, how has my concerns about Spiritdog affected my blood pressure? Bounced it up to a higher average it seems.

I confounded my own data however because during this same time I also stopped taking one pill/day of Mukta Vati, a stress reducing herbal mixture. My “before” BP was averaging ~110/65 and when I stopped taking it (and began stressing about spirit fueled by the latest diagnosis), my BP has drifted up to ~125/80, some days lower, some days higher, with morning readings almost always lower than evening readings.

One’s blood pressure matters.

From the American Heart Association: The Systolic Blood Pressure Intervention Trial, known as SPRINT, studied more than 9,300 people older than age 50 who had high blood pressure and at least one other risk factor for heart disease. By using medicines to reduce systolic blood pressure to below 120, instead of below 140:

  • rates of heart attack, heart failure and stroke went down 30 percent; and
  • rates of death from those conditions dropped nearly 25 percent.

I could start taking MV again but am going to wait a couple more weeks to see if I can practice being more conscious of my stories and let go of those that do not serve my well being.

Everyone should have a home blood pressure monitor.

It is inexpensive, reliable and offers valuable data not only about the health of our body but also insight into the workings of our brain.

Post #19 12092019

About two weeks ago, discovered another lump on Spirit’s left rear leg (he had a lump/soft tissue sarcoma on his right rear leg that was treated with surgery and radiation and so far, has not noticeably recurred). A needle biopsy showed this small lump to be non-cancerous, and consisting of inflamed tissue.

My suspicion/gut feeling is this is may be another location where cancer is attempting to get started.

Also, the lump in his jaw bone persists. Not getting bigger but not getting smaller either. This could be  a) residual dead tissue remaining from the radiation treatments he had to this location in May or b) persistent cancer in the bone of the jaw.

The veterinary oncologist recommended a wait and see approach about all of it and I basically agree – with the added provision I believe in hoping for the best but planning for the worst; which is to say, continue to treat him as if he has cancer.

So I have upped the dose of fenbendazole from 145 mg/day to 222 mg/day (the amount a 150 human would take for cancer treatment) and will do another liver health check in early January, 2020 to make sure he is handling the higher dose. If the liver is showing any signs of stress, I will drop back to the lower dose. There is no “correct dose” of course – all the uses reported in both humans and animals are anecdotal. No one knows. Given that the side effects seem to be so minimal (none noticeable in Spirit to date after three months of use), a higher dose seems worth the try.

I have also added Metatrol and Immpower, both products produced by American Biosciences to Spirit’s daily meal. I give him one capsule of each per day with his food.  (By the way, Metatrol and Metatrol Pro have identical ingredients – just a packaging/labeling difference). There is some science and quite a few scientific studies that support the supposition that the former helps fight cancer by strengthening the immune system detect and destroy cancer cells and the latter helps strengthen the immune system in general. Neither product claims to cure cancer.

American Biosciences also makes an Immpower for dogs called NK-9; it is the same product only provided in 250 mg capsules whereas Immunpower is packaged in 500 mg capsules. Since Spirit weighs 90 pounds, he would get 2 capsules of NK-9 anyway, which is the Immpower dosage – and is somewhat less expensive to buy this way.

As to Spirit, he is still doing extremely well in terms of appetite, energy and attitude – acts like a 2 year old when we are out walking.

The name of this game is to buck up, stick to the program and watch for ways to improve our game.

Post # 10 06252019

A few days ago, I brought Spirit in for a checkup at the Animal Cancer and Imaging Center in Canton, MI.

Mostly, good news.

The only bad news is it could take 6-12 months for his hair to grow back in his radiated tumor locations.

And it might not grow back completely.

What?

I don’t mind the cosmetic aspect of it – who cares – but this means these areas have less protection from cuts and abrasions that could happen out walking, or anywhere for that matter. Not thrilled about this. Also means I will have to continue indefinitely with Aloe sprays, wrapping his leg for walks, and being careful about where we walk – romps through the woods would be not too smart right now.

Otherwise, good news.

The vet could not be absolutely sure but she thought the tumor on his jaw was a soft tissue sarcoma that had begun to penetrate into the bone rather than osteosarcoma (bone cancer, originating in the bone itself and which is incurable and aggressive). She based her opinion on the CT scan – so not the definitive diagnosis one would get from an actual biopsy. As the reader may remember from earlier posts, a needle biopsy did verify a sarcoma but could not distinguish between a soft tissue sarcoma and osteosarcoma. No certainty here but, still, I choose to be optimistic.

And, no more plastic cone around his neck!!!! (By the way, early on, I modified a store bought cone with too many mostly unworkable snaps on it and had a shoemaker sew Velcro strips on it so I could take it off and put it on in a couple of seconds. Still, both Spirit and I hated that cone!)

They also said his wounds are healing nicely. No reason for concern so far.

They had no real advice about how to administer CBD – outside their area of expertise, but they did give me some nice plastic 3 ml syringes I can use to administer it.

They did not disagree with my proposed approach of giving Spirit the entire daily dose at one time.

My strategy is based on watching how nurses administered chemo drugs to Dianna (my deceased wife). Her chemo drugs were not spread out over an entire day (although one was given in a slow drip injection through a port she carried around all day because that one could damage her heart if given all at once. None of this is an issue with CBD as it has no known serious side effects other than possible drowsiness, lethargy, etc.)

So, to allow Spirit to live his normal life as much as possible, I have decided to give him his entire dose at bedtime.

My reasoning is, this approach will:

  1. a) Aid in his sleeping (one common effect of CBD is reduced anxiety and drowsiness).
  2. b) CBD + sleep could be synergistic – both have healing characteristics.
  3. c) The effects will be mostly worn off by morning and he can enjoy being his normal self all day long.

In my next post, I will detour from the practical to the spiritual, investigating why I have found so much of my life devoted to care giving cancer patients, first for my wife, now for Spirit.

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