Post # 14 07/30/2019 New Information about CBD as a Chemo Treatment

I am a paying member of Consumer Labs, www.consumerlabs.com , an on line source of information about supplements –and they just came out with a report on CBD oil and its uses that changed my thinking about when to administer it to Spirit.

Here are the major takeaways for me in this report:

  1. Most of the research into the value of using CBD oil to treat medical conditions such as cancer is done at very high doses (like 20 mg CBD per kilogram of body weight – about 800 mg/day for Spirit!)– far above my 45-50 mg/day dose I am using for Spirit. However, at these levels, one must start to be concerned about side effects, like affecting kidney function, diarrhea, vomiting, etc.
  2. To be most effective, because CBD is fat soluable, adsorption is 5-15 times higher when given with or right after a high fat meal rather than on an empty stomach! The meal should contain 500-600 calories of fat to be helpful.
  3. With a high fat meal accompanying the CBD, the half life of CBD in the body almost doubles from 24 hours to 39 hours.
  4. CBD at the levels I am giving does not materially aid in sleeping better.
  5. Preliminary science and antidotal evidence suggests CBD does have anti cancer properties and enhances the body’s immune system response to cancer.
  6. There is also early evidence it can help with seizures, pain, anxiety, inflammation and likely other ailments too. Not my focus here, so I will not go into all the data about these conditions.
  7. Half life of CBD in the body, after hitting maximum levels in 2-5 hours, is 18-32 hours and, with continued dosing, much longer than that. So daily dosing, as I am doing with Spirit, would maintain a high level of CBD essentially all the time.
  8. CBD can interact with other medications in a negative way. Too complicated to go into here but one needs to do one’s homework and consult with others before proceeding. In Spirit’s case, he is not on any other meds so clear sailing here.
  9. As to who to buy CBD from, CL offers some information that will be helpful to some I am sure. I am already satisfied I have an excellent source with Nuleaf Naturals and will stick with them.

Based on this information, I am encouraged that the dosing level and schedule is a) not going to do any harm and b) may actually do what I am hoping – that this dose may have a positive impact on cancer metastases in Spirit – no, it not nearly as high as some studies have used but it is significantly higher than the usual – and will be doing it regularly and for a long period of time so…….who knows.

I have also immediately shifted to giving him his CBD dose right after his evening meal rather than at bedtime.

I also have added two heaping tablespoons of coconut oil to his food (worth about ~400 calories of fat). Coupled with the fat content of his regular dog food (Wellness Core dry dog food + Wellness Core canned dog food to hide his daily garlic pills for fleas and ticks + cooked hamburger + boiled egg) am confident I am up in the 500-600 calorie of fat range.

Nothing left to do now but buck up, continue with the program each and every day (practice #10, bucking up).

 

Post # 10 06252019

A few days ago, I brought Spirit in for a checkup at the Animal Cancer and Imaging Center in Canton, MI.

Mostly, good news.

The only bad news is it could take 6-12 months for his hair to grow back in his radiated tumor locations.

And it might not grow back completely.

What?

I don’t mind the cosmetic aspect of it – who cares – but this means these areas have less protection from cuts and abrasions that could happen out walking, or anywhere for that matter. Not thrilled about this. Also means I will have to continue indefinitely with Aloe sprays, wrapping his leg for walks, and being careful about where we walk – romps through the woods would be not too smart right now.

Otherwise, good news.

The vet could not be absolutely sure but she thought the tumor on his jaw was a soft tissue sarcoma that had begun to penetrate into the bone rather than osteosarcoma (bone cancer, originating in the bone itself and which is incurable and aggressive). She based her opinion on the CT scan – so not the definitive diagnosis one would get from an actual biopsy. As the reader may remember from earlier posts, a needle biopsy did verify a sarcoma but could not distinguish between a soft tissue sarcoma and osteosarcoma. No certainty here but, still, I choose to be optimistic.

And, no more plastic cone around his neck!!!! (By the way, early on, I modified a store bought cone with too many mostly unworkable snaps on it and had a shoemaker sew Velcro strips on it so I could take it off and put it on in a couple of seconds. Still, both Spirit and I hated that cone!)

They also said his wounds are healing nicely. No reason for concern so far.

They had no real advice about how to administer CBD – outside their area of expertise, but they did give me some nice plastic 3 ml syringes I can use to administer it.

They did not disagree with my proposed approach of giving Spirit the entire daily dose at one time.

My strategy is based on watching how nurses administered chemo drugs to Dianna (my deceased wife). Her chemo drugs were not spread out over an entire day (although one was given in a slow drip injection through a port she carried around all day because that one could damage her heart if given all at once. None of this is an issue with CBD as it has no known serious side effects other than possible drowsiness, lethargy, etc.)

So, to allow Spirit to live his normal life as much as possible, I have decided to give him his entire dose at bedtime.

My reasoning is, this approach will:

  1. a) Aid in his sleeping (one common effect of CBD is reduced anxiety and drowsiness).
  2. b) CBD + sleep could be synergistic – both have healing characteristics.
  3. c) The effects will be mostly worn off by morning and he can enjoy being his normal self all day long.

In my next post, I will detour from the practical to the spiritual, investigating why I have found so much of my life devoted to care giving cancer patients, first for my wife, now for Spirit.

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